ZEISS LSM 880 with Airyscan: Fast Mode acquisition of microtubules in cardiomyocytes

May 9, 2016
The timelapse movie shows microtubule buckling due to cell contraction and relaxation, taken with ZEISS LSM 880 with Airyscan in Fast Mode @96fps. In this case standard confocal imaging could not provide enough SNR, resolution and speed to accurately measure the buckling of the tubulin. Adding more laser to increase the SNR of the confocal image was not possible due to photo bleaching and photo toxicity. http://www.zeiss.com/lsm880 Courtesy of P. Robison & B. Prosser, University of Pennsylvania, USA. Science publication: https://dx.doi.org/10.1126/science.aaf0659
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