Assembly of a 3D dataset with ZEISS ZEN Correlative Array Tomography http://www.zeiss.com/zen-cat The dataset shows a Z-stack of macrophages expressing the protein huntingtin. Macrophages are used as a model system for the investigation of the Huntington’s disease. An overexpression of huntingtin results in an aggregation of the protein clearly visible within the Z-stack. An antibody was used against GFP-Huntingtin to locate plaques of huntingtin within the cells (Alexa Fluor 647, red). The nucleus is shown in blue (Hoechst). Courtesy of J. Caplan, E. Kmiec and S. Modla, University of Delaware, USA.
Bugs: Outside the Box – Face-to-face with the Insect World on a Massive Scale
ZEISS & Fibics support exhibit of the Canadian Museum of Nature with Atlas 5 large area electron microscopy...
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SH-SY5Y #cells cultured on a 384 microwell plate. Five channel image at a single position using #ZEISS Celldiscoverer 7 with 20x / 0.95 objective. Extended depth of focus from Z-stack. Hoechst – Chrom
An Introduction to Live Cell Imaging
The term live cell imaging collectively refers to the technologies used to capture images of cells in a living, active state, either as individual static pictures or as time-lapse series....
New fast 5 megapixel microscope camera for routine fluorescence applications
Acquiring up to 36 frames per second at full 5 MP resolution ZEISS Axiocam 305 mono is the new 5 megapixel camera from ZEISS for high resolution imaging at fast speeds. State-of-the-art CMOS...
Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration